Sclerotherapy (Foam/Liquid)
Treatment for Varicose Veins
Typical Dosage: Polidocanol 0.5-3%, up to 10-15mL per session
Effectiveness
80%
Safety Score
75%
Clinical Trials
4
Participants
25K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
Polidocanol 0.5-3%, up to 10-15mL per session
Time to Effect
2-6 weeks
Treatment Duration
Multiple sessions (2-4)
Evidence Quality
MODERATEConfidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$200
Side Effect Mgmt:$100
Total Annual:$2,400
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$18,000/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$3,200
Cost per Remission
$3,692
Comparison vs No treatment
Cost Difference
+$2,400/year
More expensive
QALY Difference
+0.08 QALYs
Better outcomes
Dominance
No dominance
Sclerotherapy (Foam/Liquid) Outcomes
for Varicose Veins
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+75%
Remission Rate
+65%
Common Side Effects
Hyperpigmentation
+25%
Localized pain/burning
+15%
Skin ulceration
+3%
Transient visual disturbances/headache (with foam)
+7%
Allergic reactions
+0.8%
Deep Vein Thrombosis (DVT)
+0.3%
Active Clinical Trials
3 active trials recruiting for Sclerotherapy (Foam/Liquid) in Varicose Veins
Foam and Liquid Sclerotherapy With or Without Herbal Gel for Small Vein Treatment
NCT07162844ACTIVE NOT RECRUITINGNA
508 participants
INTERVENTIONAL
Kafr ash Shaykh, Egypt
Started: Sep 5, 2024
Caprini Score in Venous Surgery: a Prospective Cohort Study
NCT03041805RECRUITING
3K participants
OBSERVATIONAL
Moscow, Russia
Started: Jan 1, 2017
Observation of Pain During the Treatment of Great Saphenous Vein Using Microwave Ablation， and Analysis of Related Factors
NCT06693245RECRUITING
155 participants
OBSERVATIONAL
Chengdu, China
Started: Dec 1, 2024