Venous Stripping and Ligation
Treatment for Varicose Veins
Typical Dosage: Not applicable (surgery)
Effectiveness
80%
Safety Score
60%
Clinical Trials
13
Participants
40K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
60
DangerousModerateSafe
Treatment Details
Dosage Range
Not applicable (surgery)
Time to Effect
2-4 weeks (recovery)
Treatment Duration
Single surgery
Evidence Quality
MODERATEConfidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$0
Monitoring:$500
Side Effect Mgmt:$300
Total Annual:$8,000
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
MODERATEICER
$75,000/QALY
QALYs Gained
0.07
Outcome-Based Costs
Cost per Responder
$10,667
Cost per Remission
$11,429
Comparison vs Endovenous Laser Ablation (EVLA)
Cost Difference
+$4,000/year
More expensive
QALY Difference
-0.03 QALYs
Worse outcomes
Dominance
No dominance
Venous Stripping and Ligation Outcomes
for Varicose Veins
Efficacy Outcomes
Overall Effectiveness
+80%
Response Rate
+75%
Remission Rate
+70%
Common Side Effects
Post-operative pain
+80%
Bruising/swelling
+85%
Nerve damage (sensory loss)
+20%
Hematoma
+15%
Infection
+3%
Deep Vein Thrombosis (DVT)
+1.5%
Scarring
+100%
Active Clinical Trials
3 active trials recruiting for Venous Stripping and Ligation in Varicose Veins
Lower Limb Venous Insufficiency and the Effect of Radiofrequency Treatment Versus Open Surgery
NCT02397226ACTIVE NOT RECRUITINGNA
198 participants
INTERVENTIONAL
Linköping, Sweden +1 more
Started: Sep 1, 2014
Caprini Score in Venous Surgery: a Prospective Cohort Study
NCT03041805RECRUITING
3K participants
OBSERVATIONAL
Moscow, Russia
Started: Jan 1, 2017
Ongoing Registry of Treatment of Chronic Venous Diseases
NCT03035747RECRUITING
5K participants
OBSERVATIONAL
Saint Petersburg, Russia
Started: Jul 1, 2016
Completed Clinical Trials
5 completed trials for Venous Stripping and Ligation in Varicose Veins
FOAM-study, Cost Minimization Study Comparing Surgery Versus Duplex Guided Foam Sclerotherapy of Varicose Veins
NCT01103258COMPLETEDNA
460 participants
INTERVENTIONAL
Maastricht, Netherlands
Started: Feb 1, 2006
Market Penetration of Laser Therapy in Venous Surgery: Ziekenhuis Oost-Limburg - Ziekenhuis Maas En Kempen Center Experience
NCT03856814COMPLETED
500 participants
OBSERVATIONAL
Genk, Belgium
Started: Mar 15, 2019
Prospective Randomized Trial Comparing the New Endovenous Procedures Versus Conventional Surgery for Varicose Veins Due to Great Saphenous Vein Incompetence
NCT00621062COMPLETEDNA
540 participants
INTERVENTIONAL
Västerås, Sweden
Started: Jan 1, 2008
A New Method of Surgically Treating Varicose Veins and Venous Ulcers - a Study to Assess Clinical and Economic Value
NCT00759434COMPLETEDNA
280 participants
INTERVENTIONAL
Hull, United Kingdom
Started: Mar 1, 2004
Comparison of Treatments in Venous Insufficiency
NCT01298908COMPLETEDNA
231 participants
INTERVENTIONAL
Helsinki, Finland +1 more
Started: Oct 1, 2007