Meclizine
Treatment for Vertigo
Typical Dosage: 12.5-50 mg daily, once a day or divided doses
Effectiveness
60%
Safety Score
75%
Clinical Trials
2
Participants
5.5K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
75
DangerousModerateSafe
Treatment Details
Dosage Range
12.5-50 mg daily, once a day or divided doses
Time to Effect
30-60 minutes
Treatment Duration
Short-term for acute episodes (days), as needed
Evidence Quality
MODERATENumber Needed to Treat (NNT)
4(Treat 4 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
15(Treat 15 patients to see 1 additional serious adverse event)
Confidence Score
85%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$30
Monitoring:$1,000
Side Effect Mgmt:$10
Total Annual:$1,040
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTQALYs Gained
0.03
Outcome-Based Costs
Cost per Responder
$53.33
Meclizine Outcomes
for Vertigo
Efficacy Outcomes
Overall Effectiveness
+60%
Response Rate
+75%
Common Side Effects
Drowsiness
+25%
Dry mouth
+12%
Blurred vision
+8%
Constipation
+5%
Sources:
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov
Completed Clinical Trials
2 completed trials for Meclizine in Vertigo
Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Acute Vertigo Symptoms From Peripheral Origin
NCT02112578COMPLETEDPHASE3
292 participants
INTERVENTIONAL
Maringá, Brazil +6 more
Started: Nov 1, 2016
Treating Benign Paroxysmal Positional Vertigo (BPPV) in ED Patients
NCT00641797COMPLETEDNA
26 participants
INTERVENTIONAL
Allentown, United States
Started: Nov 1, 2006