Topical Calcineurin Inhibitors (e.g., Tacrolimus Ointment)
Treatment for Vitiligo
Typical Dosage: Apply thin film once or twice daily
Effectiveness
50%
Safety Score
35%
Clinical Trials
70
Participants
4K
Comparative Safety Scale(Higher is safer)
Cyanide☠️
Meth💀
Cigarettes🚬
Chemo☢️
Alcohol🍺
Morphine💊
Antibiotics💉
Tylenol💊
Exercise🏃
Water💧
35
DangerousModerateSafe
Treatment Details
Dosage Range
Apply thin film once or twice daily
Time to Effect
4-6 months
Treatment Duration
6-12 months or longer
Evidence Quality
HIGHNumber Needed to Treat (NNT)
9(Treat 9 patients to see 1 additional successful outcome)
Number Needed to Harm (NNH)
4(Treat 4 patients to see 1 additional serious adverse event)
Confidence Score
90%confidence in effectiveness data
Health Economics
Annual Cost of Care
Drug Cost:$600
Monitoring:$200
Side Effect Mgmt:$100
Total Annual:$900
Cost-Effectiveness Analysis
Cost-Effectiveness Rating
EXCELLENTICER
$11,250/QALY
QALYs Gained
0.08
Outcome-Based Costs
Cost per Responder
$2,250
Cost per Remission
$12,857.14
Topical Calcineurin Inhibitors (e.g., Tacrolimus Ointment) Outcomes
for Vitiligo
Efficacy Outcomes
Overall Effectiveness
+50%
Response Rate
+40%
Remission Rate
+7%
Common Side Effects
Application site burning
+30%
Application site pruritus
+15%
Erythema
+10%
Active Clinical Trials
No active trials currently recruiting for this treatment
No active trials found in ClinicalTrials.gov